HSU, HSIEN YEH,许先业,許先業,CHEN, I TSUEN,陈一村,陳一村,LIN, TUNG YI,林东毅,林東毅
申请号：
TW101119596
公开号：
TW201347767A
申请日:
2012.05.31
申请国别(地区):
TW
年份:
2013
代理人:
摘要：
The present invention provides an application of Ling Zhi-8 (LZ-8) protein, derived from an extract of Ganoderma, for inhibiting cancer cell growth by inducing a ribosomal stress in the cancer cell and preventing the association of murine double minute 2 (MDM2) protein and p53 protein, so as to activate the p53 protein and inhibit the cancer cell growth.本發明提供一種靈芝萃取物成份抑制癌細胞生長之應用,其中前述萃取物成份為Ling Zhi-8(LZ-8)蛋白,可透過引起前述癌細胞之核醣體壓力,進而防止前述癌細胞中murine double minute 2(MDM2)蛋白與p53蛋白結合,進而活化p53蛋白,以達到抑制癌細胞生長的功效。
