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CRISTAL DE SEL DE NOUVEAU DÉRIVÉ DE 3-AZABICYCLO[3.1.0]HEXANE ET SON UTILISATION PHARMACEUTIQUE
专利权人:
UBE Industries, Ltd.; LTD.;SANWA KAGAKU KENKYUSHO CO.;SANWA KAGAKU KENKYUSHO CO., LTD.
发明人:
IWAMURA Ryo,TSUZAKI Yasunori,SETOGUCHI Hiroyuki,AKAZA Hiroto,YAMAMOTO Yasuhito,TAKAMA Akira,KUNO Yuka
申请号:
EP16796577
公开号:
EP3299357A4
申请日:
2016.05.19
申请国别(地区):
EP
年份:
2018
代理人:
摘要:
Disclosed herein are a crystal comprising a compound, which has µ-opioid receptor antagonistic action, few side effects, and high safety, and having high purity and excellent physical properties (stability, solubility, etc.), and a method for producing the crystal. The crystal is a crystal of a salt comprising: a compound represented by a formula (I) [wherein R 2 is a hydrogen atom or a halogen atom, and R 1 is a group selected from the group consisting of ]; and an acid selected from the group consisting of hydrochloric acid, hydrobromic acid, and oxalic acid, or a hydrate thereof.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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