An intelligent support assembly, for example, a mobile support assembly (e.g., cart) for a dialysis machine (e.g., a peritoneal dialysis cycler), and methods for performing dialysis treatment using such an assembly. The intelligent support assembly may be configured to determine one or more properties relating to a dialysis treatment being performed on a patient using the dialysis machine, and to control one or more actions that affect the dialysis treatment based at least in part on the determined one or more properties. The cart may be configured to receive information corresponding to the one or more properties from, and transmit such information to, the dialysis machine, network access devices, sensor devices, and other devices. The controlled actions may include adjusting a height of dialysis solution or other items relative to a height of the patient, and moving the cart relative to the location of the patient.