Artur Martynov,Boris S. Farber,Sonya Sophya Farber
申请号：
US12931467
公开号：
US20120129760A1
申请日:
2011.02.01
申请国别(地区):
US
年份:
2012
代理人:
摘要：
This invention may be used in human and veterinary medicine for the creation of a drug that is effective perorally in the treatment of many viral infections, such as influenza, herpes, and cytomegalovirus.Summary of the InventionModified peptides with antiviral properties and methods for obtaining them, distinct in that in the capacity of the main active ingredient, a mixture (assembly) of oligopeptides is used that are the products of the hydrolysis of proteins with changes in their molecular charges to the opposite are used, and to obtain them, first a partial hydrolysis of protein-containing raw material is conducted, and then a process of chemical modification of the quantity of oligopeptides obtained with a change in the charge to the molecules is conducted this is used as an antiviral vehicle for the composition of the oligopeptides obtained. This quantity of modified oligopeptides is capable of slowing down the activity of the heterodimer of b-importin cells and slowing the replication of viruses whose replication cycle depends on the function of the nucleus.An assembly of modified oligopeptides based on a quasi-life, dynamic, self-organizing system that is effective in the treatment of viral infections such as influenza, herpes, and animal viruses at all stages of the development of the infectious process where other drugs are ineffective. This drug has a wide spectrum of activity and a low level of toxicity it is accessible for industrial production and effective at any stage of the viral replication cycle that depends on cell nuclei.
