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PROCEDE DE PRODUCTION DE POLYSACCHARIDE POUR UN VACCIN CONJUGUE
专利权人:
NEDERLANDS VACCININSTITUUT
发明人:
HAMIDI, AHD,BEURRET, MICHEL FRANCOIS
申请号:
CA2538691
公开号:
CA2538691C
申请日:
2004.09.10
申请国别(地区):
CA
年份:
2014
代理人:
摘要:
The present invention relates to a method for producing a polysaccharide and aconjugate vaccine comprising the polysaccharide produced according to themethod of the invention. A characteristic step in the method according to theinvention is that the pH of the culture medium is kept at a constant valuewith base or acid until adjustment with respectively base or acid is notpossible anymore. Using the method of the inven~tion, capsular polysaccharidemay be obtained in a high yield in a relatively short time. The method isstraightforward, reproducible and cost-effective.
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