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NEW TRIAZINDION DERIVATIVES AS GABAB RECEPTOR MODULATORS
专利权人:
ADDEX PHARMA S.A
发明人:
RIGUET, ERIC,CAMPO, BRICE,GIBELIN, ANTOINE,MHALLA, KARIM
申请号:
DK07825747
公开号:
DK2104670T3
申请日:
2007.11.09
申请国别(地区):
DK
年份:
2016
代理人:
摘要:
The present invention provides novel compounds of formula I wherein W 1 , W 2 , W 3 , W 4 , W 5 , B, X 1 , X 2 , X 3 , X 4 , X 5 , E and L are as defined herein; invention compounds are gamma amino butyrique acid receptor-subtype B ("GABA B ") positive allosteric modulators (enhancers), which are useful to provide methods of treating or preventing diseases or disorders, including treatment of anxiety, depression, epilepsy, schizophrenia, cognitive disorders, spasticity and skeletal muscle rigidity, spinal cord injury, multiple sclerosis, amyotrophic lateral sclerosis, cerebral palsy, neuropathic pain and craving associated with cocaine and nicotine, panic disorder, posttraumatic stress disorders, urge urinary incontinence, gastroesophageal reflux disease, transient lower oesophageal sphincter relaxations, functional gastrointestinal disorders and irritable bowel syndrome.
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中国工程科技知识中心
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http://www.ckcest.cn/home/

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