The Board of Trustees of the Leland Stanford Junior University
发明人:
Steinman Lawrence,Ruiz Pedro,Garren Hideki
申请号：
US20100754555
公开号：
US8748404(B2)
申请日:
2010.04.05
申请国别(地区):
美国
年份:
2014
代理人:
摘要：
A pro-inflammatory T cell response is specifically suppressed by the injection into a recipient of DNA encoding an autoantigen associated with autoimmune disease. The recipient may be further treating by co-vaccination with a DNA encoding a Th2 cytokine, particularly encoding IL4. In response to the vaccination, the proliferation of autoantigen-reactive T cells and the secretion of Th1 cytokines, including IL-2, IFN-γ and IL-15, are reduced.
