This specification provides the brain activation composition which contains the ginseng fruit extract as an active ingredient. The composition according to the present specification has the effect of increasing the blood flow in the brain and improving chronic fatigue syndrome. In addition, the composition according to the present specification activates the brain, and as a result, improves the accuracy of problem solving in the cognitive ability region by strengthening the connection strength between the frontal lobe and the occipital lobe and reduces the solution time. There is an effect of shortening. For this reason, the composition according to the present specification can be used as a pharmaceutical composition or a food composition for patients suffering from chronic fatigue syndrome.本明細書は、朝鮮人参の実抽出物を有効成分として含む脳活性化組成物を提供する。本明細書に係る組成物は、脳の血流量を増加させて慢性疲労症候群を改善させるという効果を奏する。また本明細書に係る組成物は、脳を活性化させ、その結果、前頭葉と後頭葉との間の連結強度を強化させることで認知能力領域における問題解決の正確度を向上させ且つ解決時間を短縮させるという効果を奏する。このため、本明細書に係る組成物は、慢性疲労症候群を患っている患者に薬学組成物又は食品組成物として使用することができる。