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New Compounds III
专利权人:
ASTRAZENECA AB
发明人:
BESIDSKI, YEVGENI,GRIFFIN, ANDREW,LABRECQUE, DENIS,JOHNSTONE, SHAWN,JONES, PAUL,KERS, INGER,NYLOEF, MARTIN,SKOGHOLM, KARIN
申请号:
ES06835882
公开号:
ES2377661T3
申请日:
2006.12.21
申请国别(地区):
ES
年份:
2012
代理人:
摘要:
A compound having the formula: (I) where: R1 is selected from nitro, cyano, halo, and acetyl; R2 is selected from phenyl, heteroaryl, phenylmethyl, and phenyloxymethyl; where R2 is optionally substituted with one or more Q substituents selected from C16 alkyl, C16 alkoxy, C16 haloalkyl, halo, C16 haloalkoxy, C37 cycloalkoxy, C37 cycloalkyl, C16 alkynyl, C37 cycloalkylalkoxy, C37 heterocycloalkyloxy, and C16 alkoxy, said (s ) substituent (s) Q being attached to the aromatic (s) and / or heteroaromatic ring (s) of R2; R3 is H or F; R4 is methyl, methoxycarbonyl or ethyl; and salts, solvates or solvated salts thereof.Un compuesto que tiene la fórmula: (I) donde: R1 es seleccionado de nitro, ciano, halo, y acetil; R2 es seleccionado de fenil, heteroaril, fenilmetil, y feniloximetil; donde R2 es opcionalmente sustituido con uno o mas sustituyentes Q seleccionados de alquilo C16, alcoxi C16, haloalquilo C16, halo, haloalcoxi C16, cicloalcoxi C37, cicloalquilo C37, alquinilo C16, cicloalquilalcoxi C37, heterocicloalquiloxi C37, y alcoxi C13alcoxi C16, dicho (s) sustituyente (s) Q estando unido (s) al anillo (s) aromatico (s) y/o heteroaromatico (s) de R2; R3 es H o F; R4 es metil, metoxicarbonil o etil; y sales, solvatos o sales solvatadas del mismo.
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