An intraorally rapidly disintegrating tablet of useful bacteria, such as bifidobacteria and lactic bacteria, excelling in tableting stability and storage stability is obtained by compression molding of a powdery mixture of useful bacteria, crystalline cellulose/light anhydrous silicic acid (vehicle produced by mixing crystalline cellulose with a small amount of light anhydrous silicic acid in slurry form and spray drying of the mixture) and starch-containing sugars (starch powder, granulated starch, granulated starch/lactose mixture, etc.) in the dry state into a tablet of about 30 to 60 N tablet hardness and 3.2 wt.% or less water content.
