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METHODS OF CONTROL AND PREVENTION OF INFLAMMATION AND REDUCTION OF INFLAMMATORY CONDITIONS AT ANIMAL COMPANIONS
专利权人:
ИНК. (US);ХИЛЛ`С ПЕТ НЬЮТРИШН
发明人:
ФРАНЦ Нолан Зебулон (US)
申请号:
RU2012153558/13
公开号:
RU2012153558A
申请日:
2011.05.09
申请国别(地区):
RU
年份:
2014
代理人:
摘要:
1. A method for controlling or preventing inflammation and / or attenuating inflammatory conditions in animal companions, comprising administering a diet containing 50-250 ppm lipoic acid, 500-2000 IU / kg vitamin E, 40-200 ppm vitamin C, 50 -300 carnitine and 1-10% calculated on the dry matter of the plant mixture. 2. The method of claim 1, wherein the diet is administered for at least two weeks. The method of claim 1 or 2, wherein the controlled, preventable, or attenuated disease is arthritis. The method of claim 1 or 2, wherein the controlled, preventable, or attenuated disease is osteoarthritis. The method of claim 1 or 2, wherein the companion animal is a dog or cat. The method according to claim 1 or 2, wherein the lipoic acid is R - (+) - lipoic acid or the racemic mixture R / S-lipoic mixture (R / S-LA) in free form or in the form of a nutritionally acceptable salt or ester. 7. The method according to claim 1 or 2, further comprising measuring the expression of inflammatory biomarkers. The method of claim 7, wherein the inflammatory biomarkers are one or more biomarkers selected from tumor necrosis factor alpha, GM colony stimulating factor, monocytic chemotactic protein-1, interferon gamma, interleukin-10, interleukin-15, interleukin-18, interleukin -2, interleukin-4, interleukin-6, interleukin-7, interleukin-8, interferon-induced gamma protein-10 and KC chemokine. 9. The use of the diet defined in any of the preceding paragraphs to obtain a pet food product for use in any of the methods according to the above paragraphs. 10. The composition described in any of the preceding paragraphs for1. Способ контроля или профилактики воспаления и/или ослабления воспалительных состояний у животных компаньонов, включающий введение рациона, содержащего 50-250 ч/млн липоевой кислоты, 500-2000 МЕ/кг витамина E, 40-200 ч/млн витамина C, 50-300 карнитина и 1-10% в расчете на сухое вещество растительной смеси.2. Способ по п.1, где рацион вводят в течение по меньшей мере дву
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