To provide a steroidal antiinflammatory agent-containing oil-in-water emulsion composition that can stably hold a steroidal anti-inflammatory agent for a long time, has excellent emulsion stability and an excellent use feeling.SOLUTION: An oil-in-water emulsion composition contains following components (A), (B), (C), (D) and (E): (A) a steroidal antiinflammatory agent 0.05 mass% or more and 0.6 mass% or less, (B) hydrophobized hydroxypropyl methylcellulose 0.01 mass% or more and 0.5 mass% or less, (C) oil solution, (D) a surfactant, and (E) water.SELECTED DRAWING: None【課題】ステロイド系抗炎症薬を長期間安定に保持でき、乳化安定性が良好で使用感も良好な、ステロイド系抗炎症剤含有水中油型乳化組成物の提供。【解決手段】以下の成分(A)、(B)、(C)、(D)及び(E)を含有する水中油型乳化組成物。(A)ステロイド系抗炎症剤 0.05質量%以上0.6質量%以下(B)疎水化ヒドロキシプロピルメチルセルロース 0.01質量%以上0.5質量%以下、(C)油剤、(D)界面活性剤、及び(E)水【選択図】なし