PROCESS FOR PREPARING ORALLY ADMINISTERED DABIGATRAN FORMULATIONS

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专利权人:

BOEHRINGER INGELHEIM INTERNATIONAL GMBH

发明人:

LANDERER, SABINE,FRIEDL, THOMAS

申请号：

NZ58686809

公开号：

NZ586868A

申请日:

2009.03.24

申请国别(地区):

NZ

年份:

2012

代理人:

摘要：

Disclosed is a process for preparing a suspension of the polymorph form I of the methanesulphonic acid salt of dabigatran etexilate, represented by general formula (I), comprising: Suspending polymorph form I of dabigatran etexilate methanesulphonate and talc together in a solution of hydroxypropylcellulose in isopropanol, wherein the preparation of the suspension is carried out at a temperature 30 degrees Celsius or below.

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