A processing method and device for packet loss compensation in video-conferencing system are provided. The method includes: when a video conference is held, judging whether terminals participating in the video conference include one or more FEC terminals, if yes, matching code stream processing capabilities of transmitting terminal and receiving terminal between FEC terminals which transmit a code stream or between an FEC terminal and an ordinary terminal which transmit code stream, and converting a data code stream transmission rate of the transmitting terminal into a bearable data code stream rate of the receiving terminal. The device includes a judgment component and a matching component. The solution enables a terminal with packet loss to activate an FEC function to compensate lost data, and also enables an ordinary terminal without packet loss to keep an original data code stream rate for communication, thereby maximally ensuring the image quality of the video-conferencing system.