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Piranodipiridinico Compound
专利权人:
EISAI RandD MANAGEMENT CO.; LTD.
发明人:
KUROKAWA, Toshiki,YOSHIDA, Yu,SHIN, Kogyoku,KOBAYASHI, Yoshihisa,FUKUMOTO, Hironori,TAKEDA, Kunitoshi,OHASHI, Yoshiaki,KOTAKE, Makoto,SHIBUGUCHI, Tomoyuki,WATANABE, Toru,KITA, Yoichi,HIROTA, Shinsuke
申请号:
PE0005742018
公开号:
PE10082018A1
申请日:
2016.11.09
申请国别(地区):
PE
年份:
2018
代理人:
摘要:
The present Invention relates to piranodipiridinicos compounds selected from the group consisting of: 9 - (2-chlorophenyl) - 7 - (pyridin-3-yl) - 6h pyrano [3,2-b: 54 - B ] dipiridin - 8 (7H) - One 2-fluoro-6 - (7 - (5 - metoxipiridin - 3 - yl) - 8 - oxo - 7.8 - dihydro - 6h pyrano [3,2-b: 5,4-b] dipiridin - 9 - yl) benzonitrile among others. Also refers to a Pharmaceutical composition.The Invention is useful for treating Epilepsy exerting an inhibitory Power of the AMPA receptor and a reduction of the depressant Action on the central nervous system.La presente invencion se refiere a compuestos piranodipiridinicos seleccionados del grupo que consiste en: 9-(2-clorofenil)-7-(piridin-3-il)-6H-pirano[3,2-b:5,4-b]dipiridin-8(7H)-ona 2-fluoro-6-(7-(5-metoxipiridin-3-il)-8-oxo-7,8-dihidro-6H-pirano[3,2-b:5,4-b]dipiridin-9-il)benzonitrilo entre otros. Refiere tambien una composicion farmaceutica. La presente invencion es util para tratar la epilepsia ejerciendo un poder inhibitorio del receptor AMPA y una reduccion de la accion depresora del sistema nervioso central.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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