The present Invention relates to piranodipiridinicos compounds selected from the group consisting of: 9 - (2-chlorophenyl) - 7 - (pyridin-3-yl) - 6h pyrano [3,2-b: 54 - B ] dipiridin - 8 (7H) - One 2-fluoro-6 - (7 - (5 - metoxipiridin - 3 - yl) - 8 - oxo - 7.8 - dihydro - 6h pyrano [3,2-b: 5,4-b] dipiridin - 9 - yl) benzonitrile among others. Also refers to a Pharmaceutical composition.The Invention is useful for treating Epilepsy exerting an inhibitory Power of the AMPA receptor and a reduction of the depressant Action on the central nervous system.La presente invencion se refiere a compuestos piranodipiridinicos seleccionados del grupo que consiste en: 9-(2-clorofenil)-7-(piridin-3-il)-6H-pirano[3,2-b:5,4-b]dipiridin-8(7H)-ona 2-fluoro-6-(7-(5-metoxipiridin-3-il)-8-oxo-7,8-dihidro-6H-pirano[3,2-b:5,4-b]dipiridin-9-il)benzonitrilo entre otros. Refiere tambien una composicion farmaceutica. La presente invencion es util para tratar la epilepsia ejerciendo un poder inhibitorio del receptor AMPA y una reduccion de la accion depresora del sistema nervioso central.