Tsurushita, Naoya,Kumar, Shankar,Kon, Shigeyuki,Tso, J. Yun
申请号：
AU2009203350
公开号：
AU2009203350B2
申请日:
2009.01.13
申请国别(地区):
AU
年份:
2014
代理人:
摘要：
The present invention provides humanized antibodies that immunospecificallyrecognize human α9 integrin. Some of these antibodies inhibit the biologicalfunctions of the α9 integrin, thereby exhibiting therapeutic effectson various disorders or diseases that are associated with α9 integrin,including cancer, e.g., the growth and metastasis of a cancer cell, and inflammatorydiseases, e.g., rheumatoid arthritis, osteoarthritis, hepatitis, bronchialasthma, fibrosis, diabetes, arteriosclerosis, multiple sclerosis, granuloma,an inflammatory bowel disease (ulcerative colitis and Crohn's disease),an autoimmune disease, and so forth.
