KUMAR, SHANKAR,TSO, J. YUN,TSURUSHITA, NAOYA,HARADA, TATSUHIRO
申请号：
EP10750953
公开号：
EP2406285A4
申请日:
2010.03.10
申请国别(地区):
EP
年份:
2012
代理人:
摘要：
The present invention provides humanized antibodies that immunospecifically recognize human 9 integrin. Some of these antibodies inhibit the biological functions of the 9 integrin, thereby exhibiting therapeutic effects on various disorders or diseases that are associated with 9 integrin, including cancer, e.g., the growth and metastasis of a cancer cell, and inflammatory diseases, e.g., rheumatoid arthritis, osteoarthritis, hepatitis, bronchial asthma, fibrosis, diabetes, arteriosclerosis, multiple sclerosis, granuloma, an inflammatory bowel disease (ulcerative colitis and Crohn's disease), an autoimmune disease, and so forth.
