A novel soybean variety, designated 5PHFW50 is provided. Also providedare the seeds of soybean variety 5PHFW50, cells from soybean variety5PHFW50, plants of soybean 5PHFW50, and plant parts of soybean variety5PHFW50. Methods provided include producing a soybean plant by crossingsoybean variety 5PHFW50 with another soybean plant, methods for introgressinga transgenic trait, a mutant trait, and/or a native trait into soybean variety5PHFW50, methods for producing other soybean varieties or plant parts derivedfrom soybean variety 5PHFW50, and methods of characterizing soybean variety5PHFW50. Soybean seed, cells, plants, germplasm, breeding lines, varieties,and plant parts produced by these methods and/or derived from soybean variety5PHFW50 are further provided.