A novel soybean variety, designated 5PRZQ77 is provided. Also providedare the seeds of soybean variety 5PRZQ77, cells from soybean variety5PRZQ77, plants of soybean 5PRZQ77, and plant parts of soybean variety5PRZQ77. Methods provided include producing a soybean plant by crossingsoybean variety 5PRZQ77 with another soybean plant, methods for introgressinga transgenic trait, a mutant trait, and/or a native trait into soybean variety5PRZQ77, methods for producing other soybean varieties or plant parts derivedfrom soybean variety 5PRZQ77, and methods of characterizing soybean variety5PRZQ77. Soybean seed, cells, plants, germplasm, breeding lines, varieties,and plant parts produced by these methods and/or derived from soybean variety5PRZQ77 are further provided.