Peter B. Dervan,Nicholas G. Nickols,Claire S. Jacobs,Michelle E. Farkas,Daniel A. Harki
申请号:
US14027073
公开号:
US09630950B2
申请日:
2013.09.13
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The present invention relates to polyamides capable of inhibiting ARE-, GRE- and ERE-mediated gene regulation in cells. The present invention also relates to polyamides capable of modulating the activity of RNA polymerase II and p53. The invention also relates to methods to treat diseases related to ARE-, GRE- and ERE-mediated gene regulation and to RNA polymerase II and p53 activity.