The present invention provides, for example, the following: aptamers having inhibitory activity on FGF2； complexes containing aptamers and functional substances (e.g., affinity substances, labeling substances, enzymes, drug delivery media or drugs, etc.) having binding activity with FGF2 and inhibitory activity against FGF2； and drugs, diagnostic reagents or labeling reagents comprising: having binding activity with FGF2 and inhibiting activity against FGF2 Or a complex containing the aptamer and the functional substance； and the like.本發明提供例如下述：具有對FGF2的抑制活性的適體；包含具有與FGF2的結合活性和對FGF2的抑制活性的適體和功能性物質（例如，親和性物質、標記物質、酶、藥物遞送介質或藥物等）的複合物；和藥物、診斷試劑或標記試劑，其包含：具有與FGF2的結合活性和對FGF2的抑制活性的適體，或包含所述適體和功能性物質的複合物；等等。
