A drug delivery device is provided comprising a cartridge holder (2) comprising at least one guide track (12), and a body (3) comprising at least one interaction member (13) adapted and arranged to mechanically cooperate with the at least one guide track. The guide track (12) comprises a first section (12A) and a second section (12B), wherein the path which is defined by the first section (12A) encloses an angle with the longitudinal axis (14) of the device, wherein the angle which is enclosed by the path defined by the first section (12A) with the longitudinal axis (14) is smaller than the angle which is enclosed by the path defined by the second section (12B) with the longitudinal axis (14), wherein, for connecting the cartridge holder (2) to the body (3), the interaction member (13) is configured to mechanically cooperate with the first section (12A) such that the cartridge holder (2) is axially moved and rotated with respect to the body (3), and the interaction member (13) is configured to mechanically cooperate with the second section (12B) such that the cartridge holder (2) is rotated with respect to the body (3), whereby an axial movement of the cartridge holder (2) with respect to the body (3) is prevented. Furthermore, a cartridge holder for a drug delivery device is provided.
