use of copper in the preparation of a foodstuff, use of said foodstuff comprising copper, and method for determining a dog's susceptibility to copper accumulation in the liver
Alan James Martin,Gaby Hoffmann,Jan Rothuizen,Paul Glyn Jones
申请号：
BRPI0818293
公开号：
BRPI0818293B1
申请日:
2008.10.03
申请国别(地区):
BR
年份:
2017
代理人:
摘要：
The present invention provides a method of determining the susceptibility of a dog to liver copper accumulation comprising detecting the presence or absence of (a) a polymorphism in the GOLGA5, ATP7a or UBL5 gene of the dog that is indicative of susceptibility to copper accumulation and/or (b) a polymorphism in linkage disequilibrium with a said polymorphism (a), and thereby determining the susceptibility of the dog to liver copper accumulation. The invention also provides a foodstuff comprising copper at a concentration of less than 21 mg/kg dry matter for use in preventing a disease attributable to liver copper accumulation in a dog having genetic inheritance of the Labrador Retriever breed.
