The present invention provides an improved cooling bag and a manufacturing method thereof that can reliably break the inner bag in the outer bag by applying a predetermined force from the outside of the outer bag, and generate an endothermic reaction quickly and surely.The cooling bag is provided with an outer bag 11 and an inner bag 12, and the powder and granular medicine 13 is contained in the outer bag 11. The inner bag 12 has a predetermined size, and water or hydrate is sealed in it and stored in the outer bag 11. By applying a predetermined force or more from the outside of the outer bag 11, the inner bag 12 is broken in the outer bag 11, and the water in the inner bag 12 flows out into the outer bag 11 and impregnates the medicine 13 to produce an endothermic reaction. In the cooling bag 10, in order to prevent the inner bag 12 from moving in the outer bag 11 when a force is applied from the outside of the outer bag 11, the outer bag 11 is provided with a non-slip portion that prevents the inner bag 12 from moving.本發明係提供：藉由從外袋的外側施加既定以上的力，而確實使外袋內的內袋破袋，迅速且確實產生吸熱反應之經改良的冷卻袋及其製造方法。冷卻袋係具備有外袋11與內袋12，在外袋11中收容著粉粒狀藥劑13。內袋12係具有既定大小，且在其中密封著水或水合物並收納於外袋11內。藉由從外袋11的外側施加既定以上的力，便在外袋11內使內袋12破袋，內袋12中的水流出至外袋11內並浸漬藥劑13產生吸熱反應。在冷卻袋10中，為當從外袋11的外側施加力時，使內袋12不會在外袋11內移動，而在外袋11中設置防止內袋12移動的防滑部。
