Modified ubiquitin proteins having a specific binding activity for the extradomain B of fibronectin

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专利权人:

Anja Kunert;Arnd Steuernagel;Thomas Goettler;Ilka Haenssgen;Manja Gloser;Erik Fiedler;Markus Fiedler;Joerg Nerkamp

发明人:

Arnd Steuernagel,Erik Fiedler,Markus Fiedler,Anja Kunert,Joerg Nerkamp,Thomas Goettler,Manja Gloser,Ilka Haenssgen

申请号：

US13142195

公开号：

US08921304B2

申请日:

2010.12.14

申请国别(地区):

US

年份:

2014

代理人:

摘要：

The present invention refers to novel hetero-multimeric proteins obtained from modified ubiquitin capable of binding the extradomain B of fibronectin (ED-B) with high affinity. Furthermore, the invention refers to fusion proteins comprising said recombinant protein fused to a pharmaceutically and/or diagnostically active component. The invention is further directed to the use of said proteins in medical treatment methods.

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