NERKAMP JOERG,BOSSE DOENECKE Eva,STEUERNAGEL ARND,FIEDLER ULRIKE,FIEDLER MARKUS
申请号:
IN76/CHENP/2014
公开号:
IN2014CN00076A
申请日:
2014.01.03
申请国别(地区):
IN
年份:
2015
代理人:
摘要:
The present invention refers to novel dimeric proteins obtained from modified ubiquitin capable of binding targets with high affinity. The novel dimeric binding proteins comprise a combination of amino acid substitutions and at least one insertion of amino acids in one of the monomers. The invention is further directed to the use of said proteins in medical diagnosis or treatment methods.