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Dimeric binding proteins based on modified ubiquitins
专利权人:
Joerg Nerkamp
发明人:
Joerg Nerkamp,Eva Bosse-Doenecke,Arnd Steuernagel,Ulrike Fiedler,Markus Fiedler
申请号:
US14126358
公开号:
US09492572B2
申请日:
2012.06.15
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The present invention refers to novel dimeric proteins obtained from modified ubiquitin capable of binding targets with high affinity. The novel dimeric binding proteins comprise a combination of amino acid substitutions and at least one insertion of amino acids in one of the monomers. The invention is further directed to the use of said proteins in medical diagnosis or treatment methods.
来源网站:
中国工程科技知识中心
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