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安定な脂溶性活性成分粒子
专利权人:
发明人:
申请号:
JP20120542603
公开号:
JP5678089(B2)
申请日:
2010.12.09
申请国别(地区):
日本
年份:
2015
代理人:
摘要:

The invention relates to a method for producing fat-soluble active principles, in particular pharmaceutical and/or dietary fat-soluble active principles, in the form of particles. The invention is characterized in that said method comprises the following steps: a) preparation of an oil-in-water emulsion comprising, in weight per cent relative to the total weight of said emulsion: between 8 and 20%, preferably between 10 and 15%, of at least one protein, between 5 and 15%, preferably between 8 and 12%, of at least one sugar, between 0.5 and 3%, preferably between 2 and 3%, of at least one inorganic salt, between 10 and 22%, preferably between 15 and 20%, of at least one fat-soluble active principle in oily form and/or dissolved in an edible oil, and qs for % of water; b) formation of essentially spherical particles by the dispersion of the oil-in-water emulsion obtained at the end of step a) in a fluid; c) addition of at least one protein cross-linking agent to the dispersion obtained at the end of step b);

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