SITE-DIRECTED MODIFICATION OF FVIII
- 专利权人:
- 发明人:
- 申请号：
- HK17100391.6
- 公开号：
- HK1226754A
- 申请日:
- 2017.01.12
- 申请国别(地区):
- HK
- 年份:
- 2017
- 代理人:
- 摘要：
- This invention relates to Factor VIII muteins that are covalently bound, at a predefined site that is not an N-terminal amine, to one or more biocompatible polymers such as polyethylene glycol. The mutein conjugates retain FVIII procoagulant activity and have improved pharmacokinetic properties.
- 来源网站：
- 中国工程科技知识中心
