SU, WEI-GUO,ZHANG, WEIHAN,YAN, XIAOQIANG,CUI, YUMIN,REN, YONGXIN,DUAN, JIFENG
申请号：
ES09743783
公开号：
ES2550245T3
申请日:
2009.05.08
申请国别(地区):
ES
年份:
2015
代理人:
摘要：
Compound of the following formula: ** Formula ** in which each of R1, R2, R5, R8, R9 and R10, independently, is H, halo, nitro, amino, cyano, hydroxy, alkyl containing 1-10 carbon atoms, alkenyl containing 2-10 carbon atoms, alkynyl containing 2-10 carbon atoms, monocyclic 6-carbon aryl, bicyclic carbon or 14-carbon tricyclic, cycloalkyl containing 3-12 carbon atoms, heterocycloalkyl 3-8 member monocyclic, 8-12 member bicyclic or 11-14 member tricyclic, 5-8 member monocyclic heteroaryl, 8-12 member bicyclic or 11-14 member tricyclic, alkoxy, alkylthio, alkylcarbonyl, carboxy , alkoxycarbonyl, aminocarbonyl or aminosulfonyl； wherein each of R3 and R4 is alkoxy； R6 is alkyl； R7 is -C (O) NRaRb, each being Ra and Rb, independently, H, alkyl, alkenyl, alkynyl, aryl, cycloalkyl, heterocycloalkyl or heteroaryl, or Ra and Rb, together with the nitrogen atom to which they are attached , represent a 3-8 member ring containing 1-3 heteroatoms； X is O； and Z is N； wherein each of the alkyl, alkenyl, alkynyl, cycloalkyl, heterocycloalkyl, aryl, heteroaryl and alkoxy includes both substituted and unsubstituted moieties, in which the substituents are selected from halo, hydroxyl, amino, cyano, nitro, mercapto, alkoxycarbonyl, amido, carboxy, alkanesulfonyl, alkylcarbonyl, carbamido, carbamyl, carboxyl, thioureido, thiocyanate, sulfonamido, alkyl, alkenyl, alkynyl, alkyloxy, aryl, heteroaryl, cycloalkyl and heterocycloalkyl.Compuesto de la siguiente fórmula: **Fórmula** en el que cada uno de R1, R2, R5, R8, R9 y R10, independientemente, es H, halo, nitro, amino, ciano, hidroxi, alquilo que contiene 1-10 átomos de carbono, alquenilo que contiene 2-10 átomos de carbono, alquinilo que contiene 2-10 átomos de carbono, arilo monocíclico de 6 carbonos, bicíclico de carbonos o tricíclico de 14 carbonos, cicloalquilo que contiene 3-12 átomos de carbono, heterocicloalquilo monocíclico de 3-8 miembros, bicíclico de 8-12 miembros o tricíclico de 11-14 miembros, heteroarilo monocíclico de 5-8
