JUNG, SUNG YOUB,KIM, JIN-SUN,JANG, MYUNG HYUN,LEE, SANG HYUN,CHOI, IN YOUNG,KWON, SE CHANG,鄭聖燁,金鎭善,張明賢,李相賢,崔仁榮,權世昌
申请号：
HK15107083.6
公开号：
HK1206280A
申请日:
2015.07.24
申请国别(地区):
HK
年份:
2016
代理人:
摘要：
The present invention relates to a composition for preventing or treating hyperlipidemia, fatty liver disease or arteriosclerosis, comprising an oxyntomodulin derivative as an active ingredient. The oxyntomodulin derivative has a high ability to activate GLP-1 receptor and glucagon receptor compared to native oxyntomodulin and has the effects of reducing the blood total cholesterol, low-density cholesterol and triglyceride levels that were increased by high-fat diet, and increasing high-density cholesterol levels and the high-density cholesterol/low-density cholesterol ratio. Thus, the oxyntomodulin derivative can be effectively used for the treatment of hyperlipidemia and related diseases.
