KWON, Se Chang,JUNG, Sung Youb,CHOI, In Young,JANG, Myung Hyun,KIM, Jin-Sun,LEE, Sang Hyun
申请号：
MX2015001218
公开号：
MX360024B
申请日:
2013.07.25
申请国别(地区):
MX
年份:
2018
代理人:
摘要：
The present invention relates to a composition for preventing or treating hyperlipidemia, fatty liver disease or arteriosclerosis, comprising an oxyntomodulin derivative as an active ingredient. The oxyntomodulin derivative has a high ability to activate GLP-1 receptor and glucagon receptor compared to native oxyntomodulin and has the effects of reducing the blood total cholesterol, low-density cholesterol and triglyceride levels that were increased by high-fat diet, and increasing high-density cholesterol levels and the high-density cholesterol/low-density cholesterol ratio. Thus, the oxyntomodulin derivative can be effectively used for the treatment of hyperlipidemia and related diseases.La presente invención se refiere a el uso de una composición que comprende un conjugado de un derivado de la oxintomodulina en la elaboración de un medicamento para prevenir o tratar la hiperlipidemia, la enfermedad del hígado graso o la arteriosclerosis.
