CHOI IN YOUNG,JUNG SUNG YOUB,KIM JIN-SUN,JANGT MYUNG HYUN,LEE SANG HYUN,KWON DE CHANG
申请号：
CL2015000177
公开号：
CL2015000177A1
申请日:
2015.01.23
申请国别(地区):
CL
年份:
2015
代理人:
摘要：
The present invention relates to a composition for preventing or treating hyperlipidemia, fatty liver disease or arteriosclerosis, comprising an oxyntomodulin derivative as an active ingredient. The oxyntomodulin derivative has a high ability to activate GLP-1 receptor and glucagon receptor compared to native oxyntomodulin and has the effects of reducing the blood total cholesterol, low-density cholesterol and triglyceride levels that were increased by high-fat diet, and increasing high-density cholesterol levels and the high-density cholesterol/low-density cholesterol ratio. Thus, the oxyntomodulin derivative can be effectively used for the treatment of hyperlipidemia and related diseases.Una composición para prevenir o tratar la hiperlipidemia, la enfermedad del hígado graso o la arteriosclerosis que comprende un derivado de la oxintomodulina como ingrediente activo.
