Therapeutic nuclease compositions and methods

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专利权人:

UNIVERSITY OF WASHINGTON

发明人:

LEDBETTER JEFFREY A.,HAYDEN-LEDBETTER MARTHA,ELKON KEITH,SUN XIZHANG

申请号：

NZ61698912

公开号：

NZ616989A

申请日:

2012.04.27

申请国别(地区):

NZ

年份:

2016

代理人:

摘要：

Disclosed are polypeptides comprising an amino acid sequence at least 90% identical to the amino acid sequence set forth in SEQ ID NOs 62, 64, 78, 80, 92, 96, 66, 68, 70, 82, 84, 86, 94 or 98 (sequences as defined in the complete specification). Also disclosed is the use of such polypeptides to treat autoimmune diseases such as systemic lupus erythematosus (SLE).

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