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Hybrid polypeptides including meningococcal fhbp sequences
专利权人:
NOVARTIS AG
发明人:
RAPPUOLI RINO,ARICO MARIA,GIULIANI MARZIA MONICA,PIZZA MARIAGRAZIA,SCARSELLI MARIA
申请号:
NZ62204810
公开号:
NZ622048A
申请日:
2010.08.27
申请国别(地区):
NZ
年份:
2015
代理人:
摘要:
Disclosed is a polypeptide comprising a first immunogenic amino acid sequence and a second immunogenic amino acid sequence, wherein the first immunogenic amino acid sequence comprises an amino acid sequence set forth in SEQ ID NO: 20, subject to the proviso that the polypeptide does not comprise an amino acid sequence set forth in SEQ ID NO: 23, wherein the sequences are as defined in the complete specification. Also disclosed is the use of said polypeptide in the preparation of a medicament for the treatment or prevention of infection by Neisseria meningitides.
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