PROBLEM TO BE SOLVED: To provide a novel composition having an ameliorating action on a reduction in higher brain function caused by brain structural disorder.SOLUTION: A composition having an ameliorating action on a reduction in higher brain function caused by brain structural disorder comprises arachidonic acid and/or a compound composed of arachidonic acid as a constituent fatty acid and docosahexaenoic acid and/or a compound composed of docosahexaenoic acid as a constituent fatty acid.SELECTED DRAWING: Figure 1COPYRIGHT: (C)2016,JPO&INPIT【課題】器質的脳障害に起因する高次脳機能の低下に対する改善作用を有する新規な組成物の提供。【解決手段】アラキドン酸及び/又はアラキドン酸を構成脂肪酸とする化合物およびドコサヘキサエン酸及び/又はドコサヘキサエン酸を構成脂肪酸とする化合物を含んで成る、器質的脳障害に起因する高次脳機能の低下に対する改善作用を有する組成物。【選択図】図1