COMPOSITION FOR THE PREVENTION, IMPROVEMENT, OR TREATMENT OF NEUROLOGICAL DISORDER INCLUDING ADIPONECTIN RECEPTOR-ACTIVATING NOVEL PEPTIDE AS ACTIVE INGREDIENT
INDUSTRY-ACADEMIC COOPERATION FOUNDATION GYEONGSANG NATIONAL UNIVERSITY
发明人:
Myeong Ok KIM
申请号：
US16033725
公开号：
US20180312540A1
申请日:
2018.07.12
申请国别(地区):
US
年份:
2018
代理人:
摘要：
A method for preventing, improving or treating a neurological disorder includes administering to a subject a composition including an adiponectin receptor-activating novel peptide as an active ingredient. The adiponectin receptor-activating novel peptide is a peptide consisting of 5 amino acids, and when the adiponectin receptor-activating novel peptide is administered to Alzheimer's model mice, the mice's behavioral changes show that memory and cognitive functions are significantly increased, and APP and amyloid beta (Aβ) proteins are significantly reduced, cytotoxicity does not occur, the proliferation rate of neurons is increased, and cell death is inhibited.
