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作為新的有生理學價值的硝酰氧基供體的N-羥基磺酰胺衍生物
专利权人:
THE JOHNS HOPKINS UNIVERSITY
发明人:
Toscano, John, P.,Brookfield, Frederick, Arthur,Cohen, Andrew, D,Courtney, Stephen, Martin,Frost, Lisa, Marie,Kalish, Vincent, Jacob
申请号:
HK13106458.7
公开号:
HK1179509B
申请日:
2013.05.31
申请国别(地区):
HK
年份:
2017
代理人:
摘要:
The invention relates to N-hydroxysulfonamide derivatives that donate nitroxyl (HNO) under physiological conditions and are useful in treating and/or preventing the onset and/or development of diseases or conditions that are responsive to nitroxyl therapy, including heart failure and ischemia/reperfusion injury. Novel N- hydroxysulfonamide derivatives release NHO at a controlled rate under physiological conditions, and the rate of HNO release is modulated by varying the nature and location of functional groups on the N-hydroxysulfonamide derivatives.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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