An ultrasound imaging system and method includes acquiring, with an ultrasound probe in a first position, a first image of a first plane including a longitudinal axis of a vessel and displaying the first image on a display device. The system and method includes acquiring, with the ultrasound probe in a second position, a second image of a second plane that intersects the longitudinal axis of the vessel at an oblique angle, where the ultrasound probe may be moved from the first position to the second position, or from the second position to the first position, by rotating the ultrasound probe about a longitudinal axis of the ultrasound probe. The system and method includes calculating a volume flow rate of the vessel based on the first image and the second image, and displaying the volume flow rate on a display device.