Spirocyclic amide derivatives of formula Iwherein ArCH2CH2NH- represents a β-adrenoceptor binding group, processes for their preparation, pharmaceutical compositions containing them, a process for preparing such pharmaceutical compositions, their use in therapy, and intermediates for use in their preparation.化學式I之螺旋環狀醯胺衍生物其中,ArCH2CH2NH-代表一β-腎上腺受體結合基團,其製備方法,含有其等之藥學組成物,一用於製備此等藥學組成物之方法,其於治療之用途,及用於其等之製備之中間產物。