The present invention relates to the pyridylpiperidine compound of formula (I), the antagonists of Shi Shi To element receptor, and treat or prevent nerve and mental illness and the plain receptor related disease of Yu Shi To with what. The invention further relates to preventing or treating the purposes in the receptor related this disease of Yu Shi To element comprising the pharmaceutical composition of these compounds and these compounds and composition.本發明涉及式(I)的吡啶基哌啶化合物，其是食慾素受體的拮抗劑，並且用於治療或預防神經和精神病症和與食慾素受體有關的疾病。本發明還涉及包含這些化合物的藥物組合物，和這些化合物與組合物在預防或治療與食慾素受體有關的這種疾病中的用途。
