The present invention relates to substituted diazepan compounds, Shi Shi To hormone receptor antagonists, and treat or prevent the receptor related nerve and psychiatric disorders and disease of Yu Shi To elements with what. The invention further relates to preventing or treating the purposes in the receptor related this kind of disease of Yu Shi To elements containing the pharmaceutical composition of these compounds and these compounds and composition.本發明涉及取代的二氮雜環庚烷化合物，其是食慾素受體拮抗劑，並且用於治療或預防與食慾素受體有關的神經性和精神性障礙和疾病。本發明還涉及含有這些化合物的藥物組合物，和這些化合物和組合物在預防或治療與食慾素受體有關的這類疾病中的用途。
