A pillbox management method includes: read a RFID tag on a pillbox with a RFID reader to obtain a serial number, in which the serial number corresponds to a medication event including a patient information, a medication time information, and a medicine information; determine if the serial number matches a medical trolley; if the serial number matches the medical trolley, then permit the pillbox to be stored on the medical trolley.一種藥盒管理方法包含:藉由讀取裝置讀取設置於藥盒上之無線射頻辨識標籤,以取得一序號,其中所述序號對應至一用藥事件,而用藥事件包含病人資訊、用藥時間資訊以及醫藥品資訊;判斷所述序號是否與醫療推車匹配;若所述序號與醫療推車匹配,則允許醫療推車存放藥盒。