Kayvan Niazi,Andrew Nguyen,Shahrooz Rabizadeh,Patrick Soon-Shiong,Stephen Charles Benz
申请号:
US15468046
公开号:
US20170312351A1
申请日:
2017.03.23
申请国别(地区):
US
年份:
2017
代理人:
摘要:
Systems and methods are presented that allow for selection of tumor neoepitopes that are then used to generate a recombinant polytope that is optimized for proper trafficking and processing. In preferred methods, the polytope is encoded in a viral expression system that is used as a therapeutic agent.