NIAZI, Kayvan,NGUYEN, Andrew,RABIZADEH, Shahrooz,SOON-SHIONG, Patrick,BENZ, Stephen Charles
申请号:
EP17815840
公开号:
EP3475434A4
申请日:
2017.03.23
申请国别(地区):
EP
年份:
2020
代理人:
摘要:
Systems and methods are presented that allow for selection of tumor neoepitopes that are then used to generate a recombinant polytope that is optimized for proper trafficking and processing. In preferred methods, the polytope is encoded in a viral expression system that is used as a therapeutic agent.