Disclosed are a self-calibration implementation method and device for a radio frequency matrix switch. The method comprises: acquiring a radio frequency signal output by a radio frequency phase-locked loop (PLL); detecting the power of the output radio frequency signal, and reading a received signal strength indicator (RSSI) value detected on a radio frequency receiving channel of a radio frequency matrix switch; and comparing the detected RSSI value on each channel with a reference value of a corresponding frequency point, and when an absolute value of a difference value of the two is less than a pre-set first threshold value, determining that a corresponding channel has completed self-calibration at a current frequency.
