HENTEMANN, MARTIN,韩特曼,韓特曼,WOOD, JILL,伍吉尔,伍吉爾,SCOTT, WILLIAM,史考特,MICHELS, MARTIN,米希尔,米希爾,CAMPBELL, ANN-MARIE,坎贝尔,坎貝爾,BULLION, ANN-MARIE,布利恩,ROWLEY, R. BRUCE,布鲁斯,布魯斯,REDMAN, ANIKO,雷德曼
申请号：
TW096145999
公开号：
TWI406662B
申请日:
2007.12.04
申请国别(地区):
TW
年份:
2013
代理人:
摘要：
This invention relates to novel 2, 3-dihydroimidazo [1, 2-c] quinazoline compounds, pharmaceutical compositions containing such compounds and the use of those compounds or compositions for phosphotidylinositol-3-kinase (PI3K) inhibition and treating diseases associated with phosphotidylinositol-3-kmase (PI3K) activity, in particular treating hyper-proliferative and/or angiogenesis disorders, as a sole agent or in combination with other active ingredients.本發明係有關新穎之2,3-二氫咪唑并[1,2-c]喹唑啉化合物、含此等化合物之醫藥組成物及使用呈單一製劑或與其他活性成分組合之彼等化合物或組成物抑制磷脂醯肌醇-3-激酶(PI3K)及治療與磷脂醯肌醇-3-激酶(PI3K)活性相關之疾病，特別是治療過度增殖及/或血管生成疾病。
