Jaspers, Stephen R.,Rixon, Mark W.,Dillon, Stacey R.,Ramsdell, Frederick J.,Krejsa, Cecile M.,Yi, Eugene C.
申请号:
AU2008364115
公开号:
AU2008364115B2
申请日:
2008.12.08
申请国别(地区):
AU
年份:
2013
代理人:
摘要:
Human anti-human IL-21 monoclonal antibodies and the hybridomas that produce them are presented. Certain of these antibodies have the ability to bind native human IL-21, a mutant recombinat IL-21 protein and/or peptide regions of human IL-21. These human anti-IL-21 antibodies are useful in therapeutic treatment of autoimmune and inflammatory diseases, particularly diseases mediated by T follicular helper cells, B cells T