Alan John Nadin,Brian John Williams,Duncan Edward Shaw,Ian Churcher,Kevin Dinnell,Martin Richard Teall,Paul Joseph Oakley,Sonia Kerrad,Susannah Williams,Timothy Harrison,ALAN JOHN NADIN,BRIAN JOHN WILLIAMS,DUNCAN EDWARD SHAW,IAN CHURC
申请号：
BRPI0211635
公开号：
BRPI0211635B1
申请日:
2002.08.16
申请国别(地区):
BR
年份:
2018
代理人:
摘要：
"Compound, pharmaceutical composition, use of a compound, and method of treating an individual suffering from or prone to Alzheimer's disease." novel sulfones of formula I: are described. The compounds modulate amyloid precursor protein processing by gamma secretase, and as a consequence are useful in the treatment or prevention of alzheimer's disease."composto, composição farmacêutica, uso de um composto, e, método de tratamento de um indivíduo sofrendo de ou propenso à doença de alzheimer". novas sulfonas de fórmula i: são descritas. os compostos modulam o processamento de proteína precursora amilóide por gama-secretase, e como conseqüência são úteis no tratamento ou na prevenção da doença de alzheimer.
