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Composition for preventing or treating neurodegenerative disease comprising flavanone as active ingredient
专利权人:
DONG-A UNIVERSITY RESEARCH FOUNDATION FOR INDUSTRY-ACADEMY COOPERATION
发明人:
JUN, MI RA,전미라,YOU, YOON JIN,유윤진,YOUN, KUM JU,윤금주,LEE, SEON AH,이선아,PARK, JI HYUN,박지현,JUN, MI RAKR,YOU, YOON JINKR,YOUN, KUM JUKR,LEE, SEON AHKR,PARK, JI HYUNKR
申请号:
KR1020160096753
公开号:
KR1018014790000B1
申请日:
2016.07.29
申请国别(地区):
KR
年份:
2017
代理人:
摘要:
The present invention relates to a pharmaceutical composition for preventing or treating degenerative brain diseases comprising a flavanone derivative as an active ingredient. Specifically, the pharmaceutical composition can be useful for preventing or treating degenerative brain diseases by inhibiting the activity of beta-secretase 1 (BACE1) to inhibit the production of beta-amyloid plaques.본 발명은 플라바논 유도체를 유효성분으로 포함하는 퇴행성 뇌질환의 예방 또는 치료용 약학적 조성물에 관한 것으로서, 구체적으로 BACE1(beta-secretase 1)의 활성을 억제하여 베타-아밀로이드 플라크의 생성을 억제하여 퇴행성 뇌질환을 예방 또는 치료하는데 유용하게 사용될 수 있다.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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